JNJ-39729209, CAS [[1160606-90-5]] Preis auf Anfrage
Artikelnummer:
MCE-HY-120476
Hersteller Artikelnummer:
HY-120476
Alternativnummer:
MCE-HY-120476-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
JNJ-39729209 is an antagonist for transient receptor potential vanilloid 1 (TRPV1) with pIC50 of 7.9, 8.5, 7.9 and 7.7 for TRPV1 from human, rat, canine and guinea pig. JNJ-39729209 inhibits Capsaicin (HY-10448)-induced hypotension and inhibit thereby hypothermia. JNJ-39729209 exhibits anti-inflammatory and analgesic activities in Carrageenan (HY-125474)- and CFA (HY-153808)-induced thermal hyperalgesia rat models. JNJ-39729209 exhibits anti-cough effects in guinea pigs[1].
Molekulargewicht:
455.28
CAS Nummer:
[1160606-90-5]
Formel:
C19H11Cl2F3N4S
Target-Kategorie:
TRP Channel
Anwendungsbeschreibung:
MCE Product type: Reference compound
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