JNJ-39729209, CAS [[1160606-90-5]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-120476
Supplier Catalog Number:
HY-120476
Alternative Catalog Number:
MCE-HY-120476-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
JNJ-39729209 is an antagonist for transient receptor potential vanilloid 1 (TRPV1) with pIC50 of 7.9, 8.5, 7.9 and 7.7 for TRPV1 from human, rat, canine and guinea pig. JNJ-39729209 inhibits Capsaicin (HY-10448)-induced hypotension and inhibit thereby hypothermia. JNJ-39729209 exhibits anti-inflammatory and analgesic activities in Carrageenan (HY-125474)- and CFA (HY-153808)-induced thermal hyperalgesia rat models. JNJ-39729209 exhibits anti-cough effects in guinea pigs[1].
Molecular Weight:
455.28
CAS Number:
[1160606-90-5]
Formula:
C19H11Cl2F3N4S
Target:
TRP Channel
Application Notes:
MCE Product type: Reference compound
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