AM-6226 is a potent and orally active G protein coupled receptor 40 (GPR40) full agonist with an EC50 of 0.12 µM. AM-6226 can activate the GPR40 receptors on pancreatic beta cells and enteroendocrine L cells, promote insulin secretion in a glucose-dependent manner and also increase the release of incretin hormones (GLP-1, GIP), thereby avoiding the risk of hypoglycemia. AM-6226 can be used for the research of metabolic disease, such as diabetes[1].
Molekulargewicht:
522.62
CAS Nummer:
[1449742-87-3]
Formel:
C32H36F2O4
Target-Kategorie:
Free Fatty Acid Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
