Prostaglandin B1 (PGB1) is a metabolite of Prostaglandin A1 (HY-113053) with anti-inflammatory properties. Prostaglandin B1 acts as a non-competitive inhibitor of 15-hydroxyprostaglandin dehydrogenase (15-PGDH). Prostaglandin B1 counteracts nanoplastics-induced mitochondrial damage, excessive activation of innate immunity and cytotoxicity, and can antagonize the activation of the cGAS-STING pathway. Prostaglandin B1 levels are negatively correlated with prolylhydroxyproline (associated with cardiac hypertrophy, systolic dysfunction and mitochondrial dysfunction) and cholesterol (accumulation of which causes lipotoxicity)[1][2][3].
Molekulargewicht:
336.47
Reinheit:
99.32
CAS Nummer:
[13345-51-2]
Formel:
C20H32O4
Target-Kategorie:
15-PGDH,Cyclic GMP-AMP Synthase,STING
Anwendungsbeschreibung:
MCE Product type: Natural Products
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
