Prostaglandin B1 (PGB1) is a metabolite of Prostaglandin A1 (HY-113053) with anti-inflammatory properties. Prostaglandin B1 acts as a non-competitive inhibitor of 15-hydroxyprostaglandin dehydrogenase (15-PGDH). Prostaglandin B1 counteracts nanoplastics-induced mitochondrial damage, excessive activation of innate immunity and cytotoxicity, and can antagonize the activation of the cGAS-STING pathway. Prostaglandin B1 levels are negatively correlated with prolylhydroxyproline (associated with cardiac hypertrophy, systolic dysfunction and mitochondrial dysfunction) and cholesterol (accumulation of which causes lipotoxicity)[1][2][3].
Molecular Weight:
336.47
Purity:
99.32
CAS Number:
[13345-51-2]
Formula:
C20H32O4
Target:
15-PGDH,Cyclic GMP-AMP Synthase,STING
Application Notes:
MCE Product type: Natural Products
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