A 62176 (hydrochloride), CAS [[111783-54-1]] Preis auf Anfrage
Artikelnummer:
MCE-HY-120750
Hersteller Artikelnummer:
HY-120750
Alternativnummer:
MCE-HY-120750-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
A 62176 hydrochloride is a compound that targets DNA topoisomerase II and has the activity of inhibiting purine synthesis in cancer cells. A 62176 hydrochloride interferes with c-MYC mRNA expression by interacting with G-quadruplex. The main mechanism of action of A 62176 hydrochloride is by displacing nucleosomes from the quadruplex of non-template strand rDNA, resulting in rapid redistribution of nucleosomes. The application potential of A 62176 hydrochloride is that it causes DNA damage and relies on BRCA1/2-mediated homologous recombination and DNA-PK-mediated non-homologous end-joining pathways to repair the damage[1].
Molekulargewicht:
417.82
CAS Nummer:
[111783-54-1]
Formel:
C20H17ClFN3O4
Target-Kategorie:
Endogenous Metabolite
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
