A 62176 (hydrochloride), CAS [[111783-54-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-120750
Supplier Catalog Number:
HY-120750
Alternative Catalog Number:
MCE-HY-120750-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
A 62176 hydrochloride is a compound that targets DNA topoisomerase II and has the activity of inhibiting purine synthesis in cancer cells. A 62176 hydrochloride interferes with c-MYC mRNA expression by interacting with G-quadruplex. The main mechanism of action of A 62176 hydrochloride is by displacing nucleosomes from the quadruplex of non-template strand rDNA, resulting in rapid redistribution of nucleosomes. The application potential of A 62176 hydrochloride is that it causes DNA damage and relies on BRCA1/2-mediated homologous recombination and DNA-PK-mediated non-homologous end-joining pathways to repair the damage[1].
Molecular Weight:
417.82
CAS Number:
[111783-54-1]
Formula:
C20H17ClFN3O4
Target:
Endogenous Metabolite
Application Notes:
MCE Product type: Reference compound
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