NCDM-32B is a potent and selective KDM4 inhibitor, with IC50 values of 3.0 µM for KDM4A and 1.0 µM for KDM4C in in vitro enzyme assays. NCDM-32B specifically increases global H3K9me3/me2 levels in basal breast cancer cells. NCDM-32B impairs the viability of KDM4C-amplified basal breast cancer cell lines (HCC1954 and Colo824). NCDM-32B can be used for the study of breast cancer[1][2].
Molekulargewicht:
302.41
Reinheit:
97
CAS Nummer:
[1239468-48-4]
Formel:
C15H30N2O4
Target-Kategorie:
Histone Demethylase
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
