SR1555 is a specific retinoic acid receptor-related orphan nuclear receptor gamma (RORgamma) inverse agonist with an IC50 value of 1 µM. SR1555 not only inhibits TH17 cell development and function but also increases the frequency of T regulatory cells, as well as inhibits the expression of IL-17. SR1555 can be used for researching autoimmune diseases[1].
Molekulargewicht:
460.41
Reinheit:
99.69
CAS Nummer:
[1386439-51-5]
Formel:
C22H22F6N2O2
Target-Kategorie:
ROR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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