SR1555 is a specific retinoic acid receptor-related orphan nuclear receptor gamma (RORgamma) inverse agonist with an IC50 value of 1 µM. SR1555 not only inhibits TH17 cell development and function but also increases the frequency of T regulatory cells, as well as inhibits the expression of IL-17. SR1555 can be used for researching autoimmune diseases[1].
Molecular Weight:
460.41
Purity:
99.69
CAS Number:
[1386439-51-5]
Formula:
C22H22F6N2O2
Target:
ROR
Application Notes:
Reference compound
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