(R)-MMP408, CAS [[1258003-93-8]]

Produktübersicht

• Artikelname: (R)-MMP408, CAS [[1258003-93-8]]
• Artikelnummer: MCE-HY-12093A
• Hersteller Artikelnummer: HY-12093A
• Alternativnummer: MCE-HY-12093A-10MG,MCE-HY-12093A-5MG,MCE-HY-12093A-1MG,MCE-HY-12093A-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

(R)-MMP408 is an isomer of MMP408 (HY-12093). MMP408 is an orally active MMP-12 inhibitor (IC50=2.0 nM for hMMP-12) that effectively interferes with the epithelial-mesenchymal transition (EMT) process. MMP408 significantly upregulates the expression of E-cadherin in nasal epithelial cells, while inhibiting mesenchymal markers such as vimentin, alpha-smooth muscle actin and fibronectin, thereby reversing the EMT phenotype. MMP408 is used in studies of airway remodeling-related diseases, including chronic rhinosinusitis with nasal polyps, chronic obstructive pulmonary disease (COPD) and asthma[1][2][3].

Produkteigenschaften

• Molekulargewicht: 420.44
• Reinheit: 99.91
• CAS Nummer: [1258003-93-8]
• Formel: C19H20N2O7S
• Target-Kategorie: Cadherin,Drug Isomer,MMP

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound