3-Hydroxyflunitrazepam, CAS [[67739-71-3]] Preis auf Anfrage

Produktübersicht

• Artikelname: 3-Hydroxyflunitrazepam, CAS [[67739-71-3]] Preis auf Anfrage
• Artikelnummer: MCE-HY-121057
• Hersteller Artikelnummer: HY-121057
• Alternativnummer: MCE-HY-121057-5MG,MCE-HY-121057-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: 3-OH FNTZ

Produktbeschreibung

3-Hydroxyflunitrazepam (3-OH FNTZ) is the major metabolite of Flunitrazepam (FNTZ), generated via 3-hydroxylation by CYP3A4 (Km = 286 µM), and represents the dominant metabolic pathway (>80%) in liver microsomes. Its formation is significantly inhibited by CYP3A4 inhibitors such as Ketoconazole (HY-B0105) (IC50 = 0.11 µM) and Ritonavir (HY-90001) (IC50 = 0.041 µM), indicating a strong dependence on CYP3A4 activity and potential drug interactions[1].

Produkteigenschaften

• Molekulargewicht: 329.28
• CAS Nummer: [67739-71-3]
• Formel: C16H12FN3O4
• Target-Kategorie: Cytochrome P450,Drug Metabolite

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound