3-Hydroxyflunitrazepam, CAS [[67739-71-3]] Preis auf Anfrage

Product Overview

• Article Name: 3-Hydroxyflunitrazepam, CAS [[67739-71-3]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-121057
• Supplier Catalog Number: HY-121057
• Alternative Catalog Number: MCE-HY-121057-5MG,MCE-HY-121057-1MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: 3-OH FNTZ

Product Description

3-Hydroxyflunitrazepam (3-OH FNTZ) is the major metabolite of Flunitrazepam (FNTZ), generated via 3-hydroxylation by CYP3A4 (Km = 286 µM), and represents the dominant metabolic pathway (>80%) in liver microsomes. Its formation is significantly inhibited by CYP3A4 inhibitors such as Ketoconazole (HY-B0105) (IC50 = 0.11 µM) and Ritonavir (HY-90001) (IC50 = 0.041 µM), indicating a strong dependence on CYP3A4 activity and potential drug interactions[1].

Product Properties

• Molecular Weight: 329.28
• CAS Number: [67739-71-3]
• Formula: C16H12FN3O4
• Target: Cytochrome P450,Drug Metabolite

Application Notes

• Application Notes: MCE Product type: Reference compound