beta2AR-IN-15, CAS [[2088234-50-6]] Preis auf Anfrage

Produktübersicht

• Artikelname: beta2AR-IN-15, CAS [[2088234-50-6]] Preis auf Anfrage
• Artikelnummer: MCE-HY-121837
• Hersteller Artikelnummer: HY-121837
• Alternativnummer: MCE-HY-121837-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

beta2AR-IN-15 is a selective beta2-adrenergic receptor (beta2AR) antagonist with a Kd of 1.7 µM. beta2AR-IN-15 binds to an intracellular beta2AR region overlapping the G-protein binding site, enhancing orthosteric inverse agonist binding while negatively modulating binding of orthosteric agonists with EC50 values of 1.9 and 0.48 µM. beta2AR-IN-15 shows inhibitory effect on cAMP production and beta-arrestin recruitment to activated beta2AR. beta2AR-IN-15 can be used for the research of cardiovascular and pulmonary diseases[1].

Produkteigenschaften

• Molekulargewicht: 647.60
• CAS Nummer: [2088234-50-6]
• Formel: C34H39BrN4O4
• Target-Kategorie: Adrenergic Receptor,Arrestin

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound