beta2AR-IN-15, CAS [[2088234-50-6]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-121837
Supplier Catalog Number:
HY-121837
Alternative Catalog Number:
MCE-HY-121837-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
beta2AR-IN-15 is a selective beta2-adrenergic receptor (beta2AR) antagonist with a Kd of 1.7 µM. beta2AR-IN-15 binds to an intracellular beta2AR region overlapping the G-protein binding site, enhancing orthosteric inverse agonist binding while negatively modulating binding of orthosteric agonists with EC50 values of 1.9 and 0.48 µM. beta2AR-IN-15 shows inhibitory effect on cAMP production and beta-arrestin recruitment to activated beta2AR. beta2AR-IN-15 can be used for the research of cardiovascular and pulmonary diseases[1].
Molecular Weight:
647.60
CAS Number:
[2088234-50-6]
Formula:
C34H39BrN4O4
Target:
Adrenergic Receptor,Arrestin
Application Notes:
MCE Product type: Reference compound
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