Lorlatinib, CAS [[1454846-35-5]]

Produktübersicht

• Artikelname: Lorlatinib, CAS [[1454846-35-5]]
• Artikelnummer: MCE-HY-12215
• Hersteller Artikelnummer: HY-12215
• Alternativnummer: MCE-HY-12215-5MG,MCE-HY-12215-50MG,MCE-HY-12215-100MG,MCE-HY-12215-10MMX1ML,MCE-HY-12215-10MG,MCE-HY-12215-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: PF-06463922

Produktbeschreibung

Lorlatinib (PF-06463922) is a selective, orally active, brain-penetrant and ATP-competitive ROS1/ALK inhibitor with anticancer activity. Lorlatinib has Kis of L1196M, respectively. Lorlatinib targets to EML4-ALK, and inhibits ALK phosphorylation with IC50s of 15-43 nM (ALKL1196), 14-80 nM (ALKG1269A), 38-50 nM (ALK1151Tins), 77-113 nM (ALKG1202R), respectively[1][2][3].

Produkteigenschaften

• Molekulargewicht: 406.41
• Reinheit: 99.92
• CAS Nummer: [1454846-35-5]
• Formel: C21H19FN6O2
• Target-Kategorie: Anaplastic lymphoma kinase (ALK),Apoptosis,ROS Kinase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound