Lorlatinib (Standard), CAS [[1454846-35-5]]

Artikelnummer: MCE-HY-12215R
Artikelname: Lorlatinib (Standard), CAS [[1454846-35-5]]
Artikelnummer: MCE-HY-12215R
Hersteller Artikelnummer: HY-12215R
Alternativnummer: MCE-HY-12215R-10MG,MCE-HY-12215R-100MG,MCE-HY-12215R-50MG,MCE-HY-12215R-25MG,MCE-HY-12215R-5MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: PF-06463922 (Standard)
Lorlatinib (Standard) is the analytical standard of Lorlatinib. This product is intended for research and analytical applications. Lorlatinib (PF-06463922) is a selective, orally active, brain-penetrant and ATP-competitive ROS1/ALK inhibitor with anticancer activity. Lorlatinib has Kis of L1196M, respectively. Lorlatinib targets to EML4-ALK, and inhibits ALK phosphorylation with IC50s of 15-43 nM (ALKL1196), 14-80 nM (ALKG1269A), 38-50 nM (ALK1151Tins), 77-113 nM (ALKG1202R), respectively[1][2][3].
Molekulargewicht: 406.41
Reinheit: 99.92
CAS Nummer: [1454846-35-5]
Formel: C21H19FN6O2
Target-Kategorie: Anaplastic lymphoma kinase (ALK),Apoptosis,Reference Standards,ROS Kinase
Anwendungsbeschreibung: MCE Product type: Reference Standards