Lorlatinib (Standard), CAS [[1454846-35-5]]

Product Overview

• Article Name: Lorlatinib (Standard), CAS [[1454846-35-5]]
• Biozol Catalog Number: MCE-HY-12215R
• Supplier Catalog Number: HY-12215R
• Alternative Catalog Number: MCE-HY-12215R-10MG,MCE-HY-12215R-100MG,MCE-HY-12215R-50MG,MCE-HY-12215R-25MG,MCE-HY-12215R-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: PF-06463922 (Standard)

Product Description

Lorlatinib (Standard) is the analytical standard of Lorlatinib. This product is intended for research and analytical applications. Lorlatinib (PF-06463922) is a selective, orally active, brain-penetrant and ATP-competitive ROS1/ALK inhibitor with anticancer activity. Lorlatinib has Kis of L1196M, respectively. Lorlatinib targets to EML4-ALK, and inhibits ALK phosphorylation with IC50s of 15-43 nM (ALKL1196), 14-80 nM (ALKG1269A), 38-50 nM (ALK1151Tins), 77-113 nM (ALKG1202R), respectively[1][2][3].

Product Properties

• Molecular Weight: 406.41
• Purity: 99.92
• CAS Number: [1454846-35-5]
• Formula: C21H19FN6O2
• Target: Anaplastic lymphoma kinase (ALK),Apoptosis,Reference Standards,ROS Kinase

Application Notes

• Application Notes: MCE Product type: Reference Standards