IWR-1, CAS [[1127442-82-3]]

Produktübersicht

• Artikelname: IWR-1, CAS [[1127442-82-3]]
• Artikelnummer: MCE-HY-12238
• Hersteller Artikelnummer: HY-12238
• Alternativnummer: MCE-HY-12238-100MG,MCE-HY-12238-5MG,MCE-HY-12238-50MG,MCE-HY-12238-10MMX1ML,MCE-HY-12238-25MG,MCE-HY-12238-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: endo-IWR 1, IWR-1-endo

Produktbeschreibung

IWR-1 (IWR-1-endo) is a tankyrase inhibitor targeting Wnt/beta-catenin (IC50 = 180 nM). IWR-1 compromises critical steps of the canonical Wnt signaling, namely translocation of beta-catenin to the nucleus and subsequent TCF/LEF activation and expression of Wnt/beta-catenin downstream targets. IWR-1 promotes beta-catenin phosphorylation by promoting stability of Axin-scaffolded destruction complexes. IWR-1 can be studied in research for anti-tumor purposes, and diseases such as osteosarcoma, colorectal cancer and psoriasis[1][2][4].

Produkteigenschaften

• Molekulargewicht: 409.44
• Reinheit: 99.60
• CAS Nummer: [1127442-82-3]
• Formel: C25H19N3O3
• Target-Kategorie: Organoid,Wnt

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound