IWR-1 (GMP), CAS [[1127442-82-3]] Preis auf Anfrage

Produktübersicht

• Artikelname: IWR-1 (GMP), CAS [[1127442-82-3]] Preis auf Anfrage
• Artikelnummer: MCE-HY-12238G
• Hersteller Artikelnummer: HY-12238G
• Alternativnummer: MCE-HY-12238G-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: endo-IWR 1 (GMP), IWR-1-endo (GMP)

Produktbeschreibung

IWR-1 (IWR-1-endo) (GMP) is the IWR-1 (HY-12238) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. IWR-1 (IWR-1-endo) is a tankyrase inhibitor targeting Wnt/beta-catenin (IC50 = 180 nM). IWR-1 compromises critical steps of the canonical Wnt signaling, namely translocation of beta-catenin to the nucleus and subsequent TCF/LEF activation and expression of Wnt/beta-catenin downstream targets. IWR-1 promotes beta-catenin phosphorylation by promoting stability of Axin-scaffolded destruction complexes. IWR-1 can be studied in research for anti-tumor purposes, and diseases such as osteosarcoma, colorectal cancer and psoriasis[1][2][4].

Produkteigenschaften

• Molekulargewicht: 409.44
• CAS Nummer: [1127442-82-3]
• Formel: C25H19N3O3
• Target-Kategorie: Organoid,Wnt

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: GMP Small Molecules