Telaglenastat (hydrochloride), CAS [[1874231-60-3]] Preis auf Anfrage

Produktübersicht

• Artikelname: Telaglenastat (hydrochloride), CAS [[1874231-60-3]] Preis auf Anfrage
• Artikelnummer: MCE-HY-12248A
• Hersteller Artikelnummer: HY-12248A
• Alternativnummer: MCE-HY-12248A-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: CB-839 (hydrochloride)

Produktbeschreibung

Telaglenastat (CB-839) hydrochloride is a first-in-class, selective, reversible and orally active glutaminase 1 (GLS1) inhibitor. Telaglenastat hydrochloride selectively inhibits GLS1 splice variants KGA (kidney-type glutaminase) and GAC (glutaminase C) compared to GLS2. The IC50s are 23 nM and 28 nM for endogenous glutaminase in mouse kidney and brain, respectively. Telaglenastat hydrochloride inudces autophagy and has antitumor activity[1].

Produkteigenschaften

• Molekulargewicht: 608.04
• CAS Nummer: [1874231-60-3]
• Formel: C26H25ClF3N7O3S
• Target-Kategorie: Autophagy,Glutaminase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound