Telaglenastat (hydrochloride), CAS [[1874231-60-3]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-12248A
Supplier Catalog Number:
HY-12248A
Alternative Catalog Number:
MCE-HY-12248A-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
CB-839 (hydrochloride)
Telaglenastat (CB-839) hydrochloride is a first-in-class, selective, reversible and orally active glutaminase 1 (GLS1) inhibitor. Telaglenastat hydrochloride selectively inhibits GLS1 splice variants KGA (kidney-type glutaminase) and GAC (glutaminase C) compared to GLS2. The IC50s are 23 nM and 28 nM for endogenous glutaminase in mouse kidney and brain, respectively. Telaglenastat hydrochloride inudces autophagy and has antitumor activity[1].
Molecular Weight:
608.04
CAS Number:
[1874231-60-3]
Formula:
C26H25ClF3N7O3S
Target:
Autophagy,Glutaminase
Application Notes:
MCE Product type: Reference compound1
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