MT-802, CAS [[2231744-29-7]]

Produktübersicht

• Artikelname: MT-802, CAS [[2231744-29-7]]
• Artikelnummer: MCE-HY-122562
• Hersteller Artikelnummer: HY-122562
• Alternativnummer: MCE-HY-122562-10MMX1ML,MCE-HY-122562-50MG,MCE-HY-122562-5MG,MCE-HY-122562-10MG,MCE-HY-122562-25MG,MCE-HY-122562-1MG,MCE-HY-122562-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

MT-802 is a BTK PROTAC degrader. MT-802 degrades wild-type BTK (DC50 = 14.6 nM) and BTK mutants including E41K, C481S (DC50 = 14.9 nM), C481R, C481Y, C481T, C481F, L528W, and inhibits their Y223 phosphorylation. BI-4732 can be used for the study of Ibrutinib (HY-10997)-resistant chronic lymphocytic leukemia (CLL). (Pink: BTK ligand (HY-150885), Blue: CRBN Ligand (HY-14658), Black: Linker (HY-141371), E3 ligase ligand-linker conjugate (HY-176340))[1][2].

Produkteigenschaften

• Molekulargewicht: 787.82
• Reinheit: 98.35
• CAS Nummer: [2231744-29-7]
• Formel: C41H41N9O8
• Target-Kategorie: Btk,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound