MT-802, CAS [[2231744-29-7]]

Product Overview

• Article Name: MT-802, CAS [[2231744-29-7]]
• Biozol Catalog Number: MCE-HY-122562
• Supplier Catalog Number: HY-122562
• Alternative Catalog Number: MCE-HY-122562-10MMX1ML,MCE-HY-122562-50MG,MCE-HY-122562-5MG,MCE-HY-122562-10MG,MCE-HY-122562-25MG,MCE-HY-122562-1MG,MCE-HY-122562-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

MT-802 is a BTK PROTAC degrader. MT-802 degrades wild-type BTK (DC50 = 14.6 nM) and BTK mutants including E41K, C481S (DC50 = 14.9 nM), C481R, C481Y, C481T, C481F, L528W, and inhibits their Y223 phosphorylation. BI-4732 can be used for the study of Ibrutinib (HY-10997)-resistant chronic lymphocytic leukemia (CLL). (Pink: BTK ligand (HY-150885), Blue: CRBN Ligand (HY-14658), Black: Linker (HY-141371), E3 ligase ligand-linker conjugate (HY-176340))[1][2].

Product Properties

• Molecular Weight: 787.82
• Purity: 98.35
• CAS Number: [2231744-29-7]
• Formula: C41H41N9O8
• Target: Btk,PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound