SKLB-C05, CAS [[2300981-68-2]] Preis auf Anfrage
Artikelnummer:
MCE-HY-122860
| Artikelname: |
SKLB-C05, CAS [[2300981-68-2]] Preis auf Anfrage |
| Artikelnummer: |
MCE-HY-122860 |
| Hersteller Artikelnummer: |
HY-122860 |
| Alternativnummer: |
MCE-HY-122860-1UNIT |
| Hersteller: |
MedchemExpress |
| Kategorie: |
Biochemikalien |
| SKLB-C05 is a novel selective, orally active TOPK inhibitor, with an IC50 of 0.5 nM. SKLB-C05 selectively inhibit TOPK kinase. SKLB-C05 induces Apoptosis, downregulates c-Myc, gamma-H2AX, activates p53, blocks FAK/Src medicated migration-related signaling. SKLB-C05 disturbs cell mitosis. SKLB-C05 shows anticancer activity only against TOPK-positive colorectal cancer[1]. |
| Molekulargewicht: |
394.89 |
| CAS Nummer: |
[2300981-68-2] |
| Formel: |
C23H23ClN2O2 |
| Target-Kategorie: |
Apoptosis,c-Myc,FAK,MDM-2/p53,Mitosis,Src,TOPK |
| Anwendungsbeschreibung: |
MCE Product type: Reference compound |
