SKLB-C05, CAS [[2300981-68-2]] Preis auf Anfrage
Catalog Number:
MCE-HY-122860
| Article Name: |
SKLB-C05, CAS [[2300981-68-2]] Preis auf Anfrage |
| Biozol Catalog Number: |
MCE-HY-122860 |
| Supplier Catalog Number: |
HY-122860 |
| Alternative Catalog Number: |
MCE-HY-122860-1UNIT |
| Manufacturer: |
MedchemExpress |
| Category: |
Biochemikalien |
| SKLB-C05 is a novel selective, orally active TOPK inhibitor, with an IC50 of 0.5 nM. SKLB-C05 selectively inhibit TOPK kinase. SKLB-C05 induces Apoptosis, downregulates c-Myc, gamma-H2AX, activates p53, blocks FAK/Src medicated migration-related signaling. SKLB-C05 disturbs cell mitosis. SKLB-C05 shows anticancer activity only against TOPK-positive colorectal cancer[1]. |
| Molecular Weight: |
394.89 |
| CAS Number: |
[2300981-68-2] |
| Formula: |
C23H23ClN2O2 |
| Target: |
Apoptosis,c-Myc,FAK,MDM-2/p53,Mitosis,Src,TOPK |
| Application Notes: |
MCE Product type: Reference compound |
