GSK-1482160 (isomer), CAS [[1695551-19-9]] Preis auf Anfrage

Produktübersicht

• Artikelname: GSK-1482160 (isomer), CAS [[1695551-19-9]] Preis auf Anfrage
• Artikelnummer: MCE-HY-123382
• Hersteller Artikelnummer: HY-123382
• Alternativnummer: MCE-HY-123382-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

GSK-1482160 isomer is the isomer of GSK-1482160 (HY-19888). GSK-1482160 is an orally active and blood-brain barrier penetrant P2X7 receptor (P2X7R) negative allosteric modulator with pIC50s of 8.5 (human) and 6.5 (rat). GSK-1482160 reduces the efficacy of ATP at the P2X7 receptor without affecting its affinity, thereby inhibiting the release of IL-1beta. GSK-1482160 is an effective radioligand and can be labeled with radioactive isotopes like 11C or 18F to image P2X7R. GSK-1482160 can be used for the studies of chronic joint pain and chronic constriction injury (CCI).

Produkteigenschaften

• Molekulargewicht: 334.72
• CAS Nummer: [1695551-19-9]
• Formel: C14H14ClF3N2O2
• Target-Kategorie: Drug Isomer

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound