GSK-1482160 (isomer), CAS [[1695551-19-9]] Preis auf Anfrage

Product Overview

• Article Name: GSK-1482160 (isomer), CAS [[1695551-19-9]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-123382
• Supplier Catalog Number: HY-123382
• Alternative Catalog Number: MCE-HY-123382-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

GSK-1482160 isomer is the isomer of GSK-1482160 (HY-19888). GSK-1482160 is an orally active and blood-brain barrier penetrant P2X7 receptor (P2X7R) negative allosteric modulator with pIC50s of 8.5 (human) and 6.5 (rat). GSK-1482160 reduces the efficacy of ATP at the P2X7 receptor without affecting its affinity, thereby inhibiting the release of IL-1beta. GSK-1482160 is an effective radioligand and can be labeled with radioactive isotopes like 11C or 18F to image P2X7R. GSK-1482160 can be used for the studies of chronic joint pain and chronic constriction injury (CCI).

Product Properties

• Molecular Weight: 334.72
• CAS Number: [1695551-19-9]
• Formula: C14H14ClF3N2O2
• Target: Drug Isomer

Application Notes

• Application Notes: MCE Product type: Reference compound