UNC2025 hydrochloride is a potent, ATP-competitive, and highly orally active Mer/Flt3 inhibitor with IC50 values of 0.74 nM and 0.8 nM, respectively. UNC2025 hydrochloride is >45-fold selectivity for MERTK relative to Axl (IC50= 122 nM, Ki = 13.3 nM). UNC2025 hydrochloride exhibits an excellent PK properties, and can be used for the investigation of acute leukemia[1].
Molekulargewicht:
513.12
Reinheit:
99.96
CAS Nummer:
[2070015-17-5]
Formel:
C28H41ClN6O
Target-Kategorie:
FLT3
Anwendungsbeschreibung:
MCE Product type: Reference compound
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