UNC2025 hydrochloride is a potent, ATP-competitive, and highly orally active Mer/Flt3 inhibitor with IC50 values of 0.74 nM and 0.8 nM, respectively. UNC2025 hydrochloride is >45-fold selectivity for MERTK relative to Axl (IC50= 122 nM, Ki = 13.3 nM). UNC2025 hydrochloride exhibits an excellent PK properties, and can be used for the investigation of acute leukemia[1].
Molecular Weight:
513.12
Purity:
99.96
CAS Number:
[2070015-17-5]
Formula:
C28H41ClN6O
Target:
FLT3
Application Notes:
MCE Product type: Reference compound
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