Anticancer agent 255, CAS [[1983924-20-4]] Preis auf Anfrage

Produktübersicht

• Artikelname: Anticancer agent 255, CAS [[1983924-20-4]] Preis auf Anfrage
• Artikelnummer: MCE-HY-123715
• Hersteller Artikelnummer: HY-123715
• Alternativnummer: MCE-HY-123715-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Anticancer agent 255 is a monocarbonylated curcumin-1,2,3-oxazole conjugate with significant anticancer activity. The IC50 values of Anticancer agent 255 in prostate cancer cells PC-3 and DU-145 are 8.8µM and 9.5µM respectively. The IC50 values of Anticancer agent 255 against breast cancer cells MCF-7, MDA-MB-231 and 4T1 are 6µM, 10µM and 6.4µM, showing good anti-cancer activity Effect. Anticancer agent 255 can induce mitochondria-mediated apoptosis in cancer cells and prevent cell cycle progression. Anticancer agent 255 down-regulated the cell proliferation marker PCNA and inhibited the activation of cell survival proteins. Anticancer agent 255 up-regulated the pro-apoptotic protein Bax and down-regulated the anti-apoptotic protein Bcl-2[1].

Produkteigenschaften

• Molekulargewicht: 492.59
• CAS Nummer: [1983924-20-4]
• Formel: C31H29FN4O
• Target-Kategorie: Apoptosis

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound