Anticancer agent 255, CAS [[1983924-20-4]] Preis auf Anfrage

Product Overview

• Article Name: Anticancer agent 255, CAS [[1983924-20-4]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-123715
• Supplier Catalog Number: HY-123715
• Alternative Catalog Number: MCE-HY-123715-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Anticancer agent 255 is a monocarbonylated curcumin-1,2,3-oxazole conjugate with significant anticancer activity. The IC50 values of Anticancer agent 255 in prostate cancer cells PC-3 and DU-145 are 8.8µM and 9.5µM respectively. The IC50 values of Anticancer agent 255 against breast cancer cells MCF-7, MDA-MB-231 and 4T1 are 6µM, 10µM and 6.4µM, showing good anti-cancer activity Effect. Anticancer agent 255 can induce mitochondria-mediated apoptosis in cancer cells and prevent cell cycle progression. Anticancer agent 255 down-regulated the cell proliferation marker PCNA and inhibited the activation of cell survival proteins. Anticancer agent 255 up-regulated the pro-apoptotic protein Bax and down-regulated the anti-apoptotic protein Bcl-2[1].

Product Properties

• Molecular Weight: 492.59
• CAS Number: [1983924-20-4]
• Formula: C31H29FN4O
• Target: Apoptosis

Application Notes

• Application Notes: MCE Product type: Reference compound