Lofepramine (hydrochloride), CAS [[26786-32-3]] Preis auf Anfrage
Artikelnummer:
MCE-HY-12390A
Hersteller Artikelnummer:
HY-12390A
Alternativnummer:
MCE-HY-12390A-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
Lopramine (hydrochloride)
Lofepramine (Lopramine) is a modified tricyclic and orally active antidepressant. Lofepramine inhibits the uptake of Noradrenaline (NA) (HY-13715) and 5-hydroxytryptamine (5-HT) with IC50s of 2.7 µM and 11 µM, respectively. Lofepramine exerts its antidepressant activity by promoting noradrenergic neurotransmission. Lofepramine also enhances serotonergic neurotransmission by inhibiting neuronal uptake of 5-HT and tryptophan pyrrolase. Lofepramine exhibits significant anxiolytic properties. [1][2][3][4].
Molekulargewicht:
455.42
CAS Nummer:
[26786-32-3]
Formel:
C26H28Cl2N2O
Target-Kategorie:
5-HT Receptor,Adrenergic Receptor
Anwendungsbeschreibung:
Reference compound
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