Lofepramine (hydrochloride), CAS [[26786-32-3]] Preis auf Anfrage

Artikelnummer: MCE-HY-12390A
Artikelname: Lofepramine (hydrochloride), CAS [[26786-32-3]] Preis auf Anfrage
Artikelnummer: MCE-HY-12390A
Hersteller Artikelnummer: HY-12390A
Alternativnummer: MCE-HY-12390A-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: Lopramine (hydrochloride)
Lofepramine (Lopramine) is a modified tricyclic and orally active antidepressant. Lofepramine inhibits the uptake of Noradrenaline (NA) (HY-13715) and 5-hydroxytryptamine (5-HT) with IC50s of 2.7 µM and 11 µM, respectively. Lofepramine exerts its antidepressant activity by promoting noradrenergic neurotransmission. Lofepramine also enhances serotonergic neurotransmission by inhibiting neuronal uptake of 5-HT and tryptophan pyrrolase. Lofepramine exhibits significant anxiolytic properties. [1][2][3][4].
Molekulargewicht: 455.42
CAS Nummer: [26786-32-3]
Formel: C26H28Cl2N2O
Target-Kategorie: 5-HT Receptor,Adrenergic Receptor
Anwendungsbeschreibung: Reference compound