Lofepramine (hydrochloride), CAS [[26786-32-3]] Preis auf Anfrage

Catalog Number: MCE-HY-12390A
Article Name: Lofepramine (hydrochloride), CAS [[26786-32-3]] Preis auf Anfrage
Biozol Catalog Number: MCE-HY-12390A
Supplier Catalog Number: HY-12390A
Alternative Catalog Number: MCE-HY-12390A-1UNIT
Manufacturer: MedchemExpress
Category: Biochemikalien
Alternative Names: Lopramine (hydrochloride)
Lofepramine (Lopramine) is a modified tricyclic and orally active antidepressant. Lofepramine inhibits the uptake of Noradrenaline (NA) (HY-13715) and 5-hydroxytryptamine (5-HT) with IC50s of 2.7 µM and 11 µM, respectively. Lofepramine exerts its antidepressant activity by promoting noradrenergic neurotransmission. Lofepramine also enhances serotonergic neurotransmission by inhibiting neuronal uptake of 5-HT and tryptophan pyrrolase. Lofepramine exhibits significant anxiolytic properties. [1][2][3][4].
Molecular Weight: 455.42
CAS Number: [26786-32-3]
Formula: C26H28Cl2N2O
Target: 5-HT Receptor,Adrenergic Receptor
Application Notes: Reference compound