TL13-112, CAS [[2229037-19-6]]

Produktübersicht

• Artikelname: TL13-112, CAS [[2229037-19-6]]
• Artikelnummer: MCE-HY-123919
• Hersteller Artikelnummer: HY-123919
• Alternativnummer: MCE-HY-123919-25MG,MCE-HY-123919-10MG,MCE-HY-123919-10MMX1ML,MCE-HY-123919-5MG,MCE-HY-123919-50MG,MCE-HY-123919-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

TL13-112 is a potent and selective ALK-PROTAC degrader and inhibits ALK activity with an IC50 value of 0.14 nM. TL13-112 also prompts the degradation of additional kinases including Aurora A, FER, PTK2 and RPS6KA1 with IC50 values of 8550 nM, 42.4 nM, 25.4 nM, and 677 nM, respectively. TL13-112 is comprised of the conjugation of Ceritinib (HY-15656) and the Cereblon ligand of Pomalidomide (HY-10984)[1].

Produkteigenschaften

• Molekulargewicht: 1002.57
• Reinheit: 98.01
• CAS Nummer: [2229037-19-6]
• Formel: C49H60ClN9O10S
• Target-Kategorie: Anaplastic lymphoma kinase (ALK),PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound