Dothiepin (Dosulepin, Dothep) is an antidepressant agent with sedative/anxiolytic activity. Dothiepin is an inhibitor preferring of noradrenaline uptake than serotonin uptake. Dothiepin facilitates noradrenergic neurotransmission via inhibiting the neuronal uptake. Dothiepin is also an antagonist of histamine H1-receptor without cardiotoxicity. Dothiepin exhibits significant analgesic activity in psychogenic facial pain,idiopathic fibromyalgia syndrome or rheumatoid arthritis[1].
Molekulargewicht:
295.44
Reinheit:
98.22
CAS Nummer:
[113-53-1]
Formel:
C19H21NS
Target-Kategorie:
5-HT Receptor,Histamine Receptor
Anwendungsbeschreibung:
Reference compound
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