HL001, CAS [[1186371-31-2]]

Artikelnummer: MCE-HY-124072
Artikelname: HL001, CAS [[1186371-31-2]]
Artikelnummer: MCE-HY-124072
Hersteller Artikelnummer: HY-124072
Alternativnummer: MCE-HY-124072-25MG,MCE-HY-124072-10MG,MCE-HY-124072-5MG,MCE-HY-124072-50MG,MCE-HY-124072-100MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
HL001 is an orally active small molecule inhibitor of Cyclophilin A (CypA) and a receptor antagonist of Lysophosphatidic acid 1 (LPA1). HL001 induces cell cycle arrest and apoptosis of tumor cells by p53. HL001 stabilizes p53 by down-regulating G3BP1, inducing reactive oxygen species and DNA damage. HL001 disrupts the interaction between MDM2 and p53-72R in a CypA dependent manner. HL001 has antitumor activity. HL001 can also be used to study pulmonary fibrosis[1][2].
Molekulargewicht: 360.36
Reinheit: 98.90
CAS Nummer: [1186371-31-2]
Formel: C21H16N2O4
Target-Kategorie: Apoptosis,Cyclophilin,LPL Receptor,MDM-2/p53,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung: MCE Product type: Reference compound