DS-437, CAS [[1674364-87-4]]

Produktübersicht

• Artikelname: DS-437, CAS [[1674364-87-4]]
• Artikelnummer: MCE-HY-124131
• Hersteller Artikelnummer: HY-124131
• Alternativnummer: MCE-HY-124131-10MG,MCE-HY-124131-25MG,MCE-HY-124131-5MG,MCE-HY-124131-100MG,MCE-HY-124131-10MMX1ML,MCE-HY-124131-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

DS-437 is a dual PRMT5/7 inhibitor (IC50s of PRMT5/7=6 µM). DS-437 is selective for PRMT5 and PRMT7 over 29 other human protein-, DNA-, and RNA-methyltransferases. DS-437 is a S-adenosylmethionine (SAM)-competitive inhibitor of PRMT5. DS-437 also inhibits DNMT3A and DNMT3B, with IC50s of 52 and 62 µM, respectively. DS-437 inhibits the methylation of FOXP3[1][2].

Produkteigenschaften

• Molekulargewicht: 397.45
• Reinheit: 99.22
• CAS Nummer: [1674364-87-4]
• Formel: C15H23N7O4S
• Target-Kategorie: Histone Methyltransferase

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound