DS-437, CAS [[1674364-87-4]]

Product Overview

• Article Name: DS-437, CAS [[1674364-87-4]]
• Biozol Catalog Number: MCE-HY-124131
• Supplier Catalog Number: HY-124131
• Alternative Catalog Number: MCE-HY-124131-25MG,MCE-HY-124131-10MG,MCE-HY-124131-50MG,MCE-HY-124131-5MG,MCE-HY-124131-100MG,MCE-HY-124131-10MMX1ML
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

DS-437 is a dual PRMT5/7 inhibitor (IC50s of PRMT5/7=6 µM). DS-437 is selective for PRMT5 and PRMT7 over 29 other human protein-, DNA-, and RNA-methyltransferases. DS-437 is a S-adenosylmethionine (SAM)-competitive inhibitor of PRMT5. DS-437 also inhibits DNMT3A and DNMT3B, with IC50s of 52 and 62 µM, respectively. DS-437 inhibits the methylation of FOXP3[1][2].

Product Properties

• Molecular Weight: 397.45
• Purity: 99.22
• CAS Number: [1674364-87-4]
• Formula: C15H23N7O4S
• Target: Histone Methyltransferase

Application Notes

• Application Notes: MCE Product type: Reference compound