N-Octadecyl-N-propyl-sulfamide, CAS [[925891-74-3]] Preis auf Anfrage

Artikelnummer: MCE-HY-124399
Artikelname: N-Octadecyl-N-propyl-sulfamide, CAS [[925891-74-3]] Preis auf Anfrage
Artikelnummer: MCE-HY-124399
Hersteller Artikelnummer: HY-124399
Alternativnummer: MCE-HY-124399-1MG,MCE-HY-124399-5MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Peroxisome proliferator-activated receptors (PPARs) play an important role in regulating lipid and glucose metabolism, and oleoylethanolamide (OEA) is a natural ligand for PPARalpha. N-Octadecyl-N-propyl-sulfamide is an analog of OEA and a potent activator of PPARalpha, with selective binding affinity for PPARalpha (EC50=100 nM, compared to 120 nM for OEA). N-Octadecyl-N-propyl-sulfamide (10 mg/kg, ip) inhibits food intake and reduces body weight gain in rats. At a dose of 1 mg/kg, N-Octadecyl-N-propyl-sulfamide induces satiety, thereby reducing food intake, body weight, and plasma triglyceride concentrations in free-feeding Wistar rats and obese Zucker (fa/fa) rats.
Molekulargewicht: 390.67
CAS Nummer: [925891-74-3]
Formel: C21H46N2O2S
Target-Kategorie: Endogenous Metabolite,PPAR
Anwendungsbeschreibung: MCE Product type: Reference compound