N-Octadecyl-N-propyl-sulfamide, CAS [[925891-74-3]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-124399
Supplier Catalog Number:
HY-124399
Alternative Catalog Number:
MCE-HY-124399-1MG,MCE-HY-124399-5MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Peroxisome proliferator-activated receptors (PPARs) play an important role in regulating lipid and glucose metabolism, and oleoylethanolamide (OEA) is a natural ligand for PPARalpha. N-Octadecyl-N-propyl-sulfamide is an analog of OEA and a potent activator of PPARalpha, with selective binding affinity for PPARalpha (EC50=100 nM, compared to 120 nM for OEA). N-Octadecyl-N-propyl-sulfamide (10 mg/kg, ip) inhibits food intake and reduces body weight gain in rats. At a dose of 1 mg/kg, N-Octadecyl-N-propyl-sulfamide induces satiety, thereby reducing food intake, body weight, and plasma triglyceride concentrations in free-feeding Wistar rats and obese Zucker (fa/fa) rats.
Molecular Weight:
390.67
CAS Number:
[925891-74-3]
Formula:
C21H46N2O2S
Target:
Endogenous Metabolite,PPAR
Application Notes:
MCE Product type: Reference compound
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