NEO214, CAS [[1361198-80-2]]

Produktübersicht

• Artikelname: NEO214, CAS [[1361198-80-2]]
• Artikelnummer: MCE-HY-124582
• Hersteller Artikelnummer: HY-124582
• Alternativnummer: MCE-HY-124582-10MG,MCE-HY-124582-100MG,MCE-HY-124582-25MG,MCE-HY-124582-50MG,MCE-HY-124582-10MMX1ML,MCE-HY-124582-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

NEO214 is an autophagy inhibitor and a covalent conjugate of the PDE4 inhibitor Rolipram (HY-16900) and perillyl alcohol (HY-N7000). It has anti-cancer activity and blood-brain barrier (BBB) permeability. Over sex. NEO214 prevents autophagy-lysosome fusion, thereby blocking autophagic flux and triggering glioma cell death. The process involves mTOR activation, andTFEB(Transcription Factor EB) aggregation. NEO214 inhibitionMacroautophagy/autophagy in glioblastoma cells has the potential to overcome chemotherapy resistance in glioblastoma[1].

Produkteigenschaften

• Molekulargewicht: 453.57
• Reinheit: 98
• CAS Nummer: [1361198-80-2]
• Formel: C27H35NO5
• Target-Kategorie: Autophagy,mTOR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound