NEO214, CAS [[1361198-80-2]]

Product Overview

• Article Name: NEO214, CAS [[1361198-80-2]]
• Biozol Catalog Number: MCE-HY-124582
• Supplier Catalog Number: HY-124582
• Alternative Catalog Number: MCE-HY-124582-10MG,MCE-HY-124582-100MG,MCE-HY-124582-25MG,MCE-HY-124582-50MG,MCE-HY-124582-10MMX1ML,MCE-HY-124582-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

NEO214 is an autophagy inhibitor and a covalent conjugate of the PDE4 inhibitor Rolipram (HY-16900) and perillyl alcohol (HY-N7000). It has anti-cancer activity and blood-brain barrier (BBB) permeability. Over sex. NEO214 prevents autophagy-lysosome fusion, thereby blocking autophagic flux and triggering glioma cell death. The process involves mTOR activation, andTFEB(Transcription Factor EB) aggregation. NEO214 inhibitionMacroautophagy/autophagy in glioblastoma cells has the potential to overcome chemotherapy resistance in glioblastoma[1].

Product Properties

• Molecular Weight: 453.57
• Purity: 98
• CAS Number: [1361198-80-2]
• Formula: C27H35NO5
• Target: Autophagy,mTOR

Application Notes

• Application Notes: MCE Product type: Reference compound