LMP-420 is a selective tumor necrosis factor-alpha (TNF-alpha) inhibitor. LMP-420 reduces the release of pro-inflammatory cytokines (e.g., IL-1beta, IL-2), inducing the expression of anti-inflammatory cytokine IL-10 and anti-apoptotic molecules SOCS-1 and Mn-SOD. LMP-420 also downregulates chemokines (e.g., IP-10, MCP-1) to reduce immune cell infiltration. LMP-420 is promising for research of type 1 diabetes mellitus, inflammatory diseases (e.g., colitis), and HIV-Mycobacterium tuberculosis coinfection[1].
Molekulargewicht:
283.52
CAS Nummer:
[473870-63-2]
Formel:
C10H15BClN5O2
Target-Kategorie:
Interleukin Related,TNF Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
