delta-Secretase inhibitor 11, CAS [[842964-18-5]]

Produktübersicht

• Artikelname: delta-Secretase inhibitor 11, CAS [[842964-18-5]]
• Artikelnummer: MCE-HY-124832
• Hersteller Artikelnummer: HY-124832
• Alternativnummer: MCE-HY-124832-25MG,MCE-HY-124832-10MG,MCE-HY-124832-50MG,MCE-HY-124832-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

delta-Secretase inhibitor 11 (compound 11) is an orally active, potent, BBB-penetrated, non-toxic, selective and specific delta-secretase inhibitor, with an IC50 of 0.7 µM. delta-Secretase inhibitor 11 interacts with both the active site and allosteric site of delta-secretase. delta-Secretase inhibitor 11 attenuates tau and APP (amyloid precursor protein) cleavage. delta-Secretase inhibitor 11 ameliorates synaptic dysfunction and cognitive impairments in tau P301S and 5XFAD transgenic mouse models. delta-Secretase inhibitor 11 can be used for Alzheimers disease research[1].

Produkteigenschaften

• Molekulargewicht: 220.23
• Reinheit: 99.89
• CAS Nummer: [842964-18-5]
• Formel: C10H12N4O2
• Target-Kategorie: Amyloid-beta,Caspase

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound