PolyQ aggregation inhibitor C2-8, CAS [[300670-16-0]] Preis auf Anfrage

Produktübersicht

• Artikelname: PolyQ aggregation inhibitor C2-8, CAS [[300670-16-0]] Preis auf Anfrage
• Artikelnummer: MCE-HY-125172
• Hersteller Artikelnummer: HY-125172
• Alternativnummer: MCE-HY-125172-5MG,MCE-HY-125172-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: Polyglutamine Aggregation inhibitor III

Produktbeschreibung

C2-8 is an inhibitor of polyglutamine (polyQ) aggregation (IC50s=25 and 0.05 µM for recombinant HDQ51 and in PC12 cells, respectively). It also inhibits polyQ aggregation in organotypic hippocampal slice cultures isolated from R6/2 transgenic mice and reduces neurodegeneration in a dose-dependent manner in a Drosophila model of Huntingtons disease. C2-8 (100 and 200 mg/kg) reduces huntingtin aggregate size, reduces neuronal atrophy, and improves motor performance in a rotarod test in the R6/2 transgenic mouse model of Huntingtons disease.

Produkteigenschaften

• Molekulargewicht: 510.20
• Reinheit: 99.9
• CAS Nummer: [300670-16-0]
• Formel: C19H14Br2N2O3S
• Target-Kategorie: Huntingtin

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound