Astemizole (R 43512), a second-generation antihistamine agent to diminish allergic symptoms with a long duration of action, is a histamine H1-receptor antagonist, with an IC50 of 4 nM. Astemizole also shows potent hERG K+ channel blocking activity with an IC50 of 0.9 nM. Astemizole has antipruritic effects[1][2].
Molekulargewicht:
458.57
Reinheit:
99.77
CAS Nummer:
[68844-77-9]
Formel:
C28H31FN4O
Target-Kategorie:
Histamine Receptor,Potassium Channel
Anwendungsbeschreibung:
MCE Product type: Reference compound
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