Wiskostatin, CAS [[253449-04-6]]

Produktübersicht

• Artikelname: Wiskostatin, CAS [[253449-04-6]]
• Artikelnummer: MCE-HY-12534
• Hersteller Artikelnummer: HY-12534
• Alternativnummer: MCE-HY-12534-50MG,MCE-HY-12534-25MG,MCE-HY-12534-100MG,MCE-HY-12534-5MG,MCE-HY-12534-10MG,MCE-HY-12534-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Wiskostatin is a potent and selective inhibitor of neuronal Wiskott-Aldrich syndrome protein (N-WASP)-mediated actin polymerization by stabilization of the closed, autoinhibited conformation, thereby preventing Arp2/3 complex activation. Wiskostatin is also a dynamin inhibitor with an IC50 value of 20.7 µM and a potent inhibitor of clathrin-mediated endocytosis with an IC50 value of 6.9 µM. Wiskostatin causes a rapid, profound, and irreversible decrease in cellular ATP levels. Wiskostatin also induces disassembly of podosomes in a murine monocyte cell line[1][2][3][4][5].

Produkteigenschaften

• Molekulargewicht: 426.15
• Reinheit: 99.87
• CAS Nummer: [253449-04-6]
• Formel: C17H18Br2N2O
• Target-Kategorie: Arp2/3 Complex

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound