TH251, CAS [[1622059-04-4]] Preis auf Anfrage

Produktübersicht

• Artikelname: TH251, CAS [[1622059-04-4]] Preis auf Anfrage
• Artikelnummer: MCE-HY-125444
• Hersteller Artikelnummer: HY-125444
• Alternativnummer: MCE-HY-125444-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

TH251 is a LIMK1 and LIMK2 inhibitor with IC50s of 52 nM and 47 nM against LIMK1 and LIMK2, respectively. TH251 binds to inactive alphaC-out and DFG-out LIMK1 conformations, inhibits unphosphorylated LIMK1 and LIMK2 enzymatic activity, and exhibits unchanged potency despite PAK-mediated phosphorylation of either kinase. TH251 can be used for the research of cancers, glaucoma, and CNS diseases[1][2].

Produkteigenschaften

• Molekulargewicht: 394.49
• CAS Nummer: [1622059-04-4]
• Formel: C22H22N2O3S
• Target-Kategorie: LIM Kinase (LIMK)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound