Pittsburgh Compound B, CAS [[566169-93-5]]

Produktübersicht

• Artikelname: Pittsburgh Compound B, CAS [[566169-93-5]]
• Artikelnummer: MCE-HY-126192
• Hersteller Artikelnummer: HY-126192
• Alternativnummer: MCE-HY-126192-10MMX1ML,MCE-HY-126192-5MG,MCE-HY-126192-10MG,MCE-HY-126192-25MG,MCE-HY-126192-50MG,MCE-HY-126192-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: PiB, 6-OH-BTA-1

Produktbeschreibung

Pittsburgh Compound B (PiB) is a blood-brain barrier-permeable, specific Abeta deposition PET tracer that binds to Abeta(1-40) fibrils with a Ki value of 678.4 nM. Through click chemical modification (a clickable Pittsburgh Compound B derivative is prepared by introducing a PEG3 linker and an alkynyl group at the 6-hydroxy site of Pittsburgh Compound B, followed by covalent conjugation with azide-labeled fluorescent dyes or affinity tags via copper-catalyzed azide-alkyne cycloaddition (CuAAC)), Pittsburgh Compound B and its conjugates can be used for fluorescence imaging, ultrastructural studies, and enrichment and characterization of Abeta complexes. Pittsburgh Compound B is applicable to Alzheimers disease research[1][2].

Produkteigenschaften

• Molekulargewicht: 256.33
• Reinheit: 98
• CAS Nummer: [566169-93-5]
• Formel: C14H12N2OS
• Target-Kategorie: Amyloid-beta

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound